ISSLS BASIC SCIENCE RESEARCH GRANT

Applications for the 2025 Basic Science Research Grant are now open.

Submission Deadline: 28th February 2025

Previous winner (sponsored by Kaken Pharmaceutical Co., Ltd and Seikagaku Corporation)

  • 2023: Dr Stefan Dudli, the Center of Experimental Rheumatology, University of Zurich, Switzerland.

Title: Bacteria-induced trained immunity in disc cells of Modic changes. Read Report

Previous winners (formally the ISSLS Research Grant, sponsored by Taisho Pharmaceutical)

  • 2022: Dr Frances Bach, Utrecht University, Department of Clinical Science, Faculty of Veterinary Medicine, The Netherlands, was awarded the Research Grant. As she has now left that institution, Josette van Maanen has continued the project and presented her progress report at the Fellowship Ceremony of the ISSLS Annual Meeting, combined with Spineweek, in Melbourne, Australia.
    Title: The effect of notochordal extracellular vesicles on human and bovine nucleus pulpous explants. Read Report

  • 2020: Dr Graciosa P. Teixeira, Institute of Orthopaedic Research and Biomechanics, Ulm University, Ulm, Germany.
    Title: Does complement deficiency influence intervertebral disc phenotype? Insights from C6 and CD59 deficient mice organ culture investigations. Read Report

  • 2019: Dr Olga Krupkova, Laboratory for Immunoengineering and Regenerative Medicine, Zurich, Switzerland.
    Title: Cell-based delivery of GDF-5 for regeneration of the intervertebral disc using CRISPR. Read Report

  • 2018: Hugo Massé-Alarie, The University of Queensland, Australia. Read Final Report, Read Progress Report

2024 BASIC SCIENCE RESEARCH GRANT WINNERS: CLARA RUIZ-FERNANDEZ & JORDY SCHOL

The ISSLS Research Grant Award Committee is pleased to announce that the winners of the 2024 Basic Science Research Grant Award (sponsored by Kaken Pharmaceutical Co., Ltd and Seikagaku Corporation) are Clara Ruiz-Fernandez & Jordy Schol, from Tokai University School of Medicine, Japan.

Both will attend the 2025 ISSLS Annual Meeting in Atlanta, where he will present his Progress Report at the Fellowship Awards Ceremony.

Congratulations to Clara Ruiz-Fernandez & Jordy Schol and their team for an outstanding submission.

Title: Unraveling Adipose Tissue Dysfunction: Investigating the Pro-inflammatory Mechanisms Driving Nucleus Pulposus Cell Degeneration in the Context of Obesity and Type 2 Diabetes.

Description: The research proposal should be in the field of basic science (including biomechanical science). At least one investigator must be a current ISSLS member. The research proposal will be judged on significance, quality of the hypothesis, experimental protocol and feasibility. Projects that intend to use the ISSLS funding to lead to other larger funding sources are encouraged but must have a strong plan for further funding. The winning proposal will receive a US$20,000.00 award. The principal investigator must be 45 years of age or younger. The research funds cannot be used as a salary for any of the investigators. The recipient will provide a written progress report to the Research Grant Committee, four weeks prior to the following year’s Annual Meeting and make a presentation during the Fellowship Ceremony of that Annual Meeting.

The announcement of the 2025 winner will be made at the ISSLS Annual Meeting in Atlanta, USA, May 12-16 2025, during the Fellowship Ceremony. At the same Fellowship Meeting, the winner of the 2024 Research Grant will make their presentation.

The winner of the 2025 award is required to attend the 2026 Annual Meeting. Exceptions to this condition will only be considered in very extraordinary circumstances.

Funding:

The ISSLS Basic Science Research Grant is for US$20,000 per year. Research costs, only, will be covered by the award. No indirect/overhead costs will be covered by the award.

The award will be judged by the Research Grant Committee:

ISSLS Secretary – Daisuke Sakai (Chair)
ISSLS President – Peter Robertson
1st Vice President – Yong Hai
2nd Vice President – Jeffrey Lotz
Scientific Representatives – Karin Wuertz-Kozak, Sibylle Grad, Koichi Sairyo

Proposal Format:

  • Background, Identification of Critical Lack of Knowledge, Preliminary Data, Significance, Hypothesis, Specific Aims: 2 page limit

  • Detailed Experimental Protocol to achieve each specific aim with expected findings and possible interpretations, pitfalls: 5 page limit

  • Further funding plans: 1 page limit

  • Reference: No limit

  • Brief biography indicating the qualifications to perform the research of Principal Investigator and all Co-investigators (1 page limit per person).

  • Curriculum Vitae of Principal Investigator and Co-investigators should be included

  • Statement that the applicant, if they win the award and accept the prize money, will attend the ISSLS Annual Meeting in Cape Town, South Africa 2026 to present their progress report and receive their certificate at the Fellowship Ceremony

E-mail the application documentation as a single PDF document together with the completed Application Form to the ISSLS Administrative office: ISSLS@asnevents.net.au.